

Pleth Variability Index (PVI®) is a breakthrough measurement that may help clinicians noninvasively and continuously assess fluid status of patients.
Clinical Applications
- > Fluid administration is critical to optimizing patient status.1
- > Traditional methods to guide fluid administration often fail to predict fluid responsiveness.2
- > Newer methods may accurately predict responsiveness but are invasive or costly.3
- > PVI has been shown to help clinicians predict fluid responsiveness in mechanically ventilated patients under general anesthesia during surgery and in the ICU.4,5
- > PVI has been shown to help clinicians improve fluid management and decrease lactate levels compared to standard care.6
"PVI demonstrated high accuracy in discriminating fluid responders from non-responders—providing a unique opportunity to better manage a patient’s fluid volume to optimize cardiac performance and organ perfusion."
Maxime Cannesson, MD
Associate Professor of Anesthesiology in the Department of Anesthesiology
& Perioperative Care at the University of California, Irvine
> Dr. Maxime Cannesson on the clinical value of PVI
Technology Platform
Masimo rainbow SET® is a noninvasive monitoring platform enabling the assessment of multiple blood constituents and physiologic parameters that previously required invasive or complicated procedures, in addition to providing Masimo SET® Measure-through Motion and Low Perfusion pulse oximetry.

- > Acoustic Respiration Rate (RRa™)
- > Carboxyhemoglobin (SpCO®)
- > Methemoglobin (SpMet®)
- > Oxygen Content (SpOC™)
- > Pleth Variability Index (PVI®)
- > Total Hemoglobin (SpHb®)
- > Oxygen Saturation (SpO2)
- > Pulse Rate (PR)
- > Perfusion Index (PI)
The upgradeable rainbow SET® platform lets you choose the rainbow® measurements that are right for you now and be confident that your investment in patient safety won’t become obsolete tomorrow.
PDF Resources
REFERENCES
- 1 Perel A. Anaesth Analg. 2008;106(4):1031-33.
- 2 Michard F. et al. Chest. 2002;121(6):2000-08.
- 3 Joshi G. et al. Anaesth Analg. 2005;101:601-5.
- 4 Cannesson M. et al. Br J Anaesth. 2008;101(2):200-6.
- 5 Loupec T. et al. Crit Care Med. 2011;39(2):294-299.
- 6 Forget P. et al. Anesth Analg. 2010;111(4):910-4.





